Horizon Scanning Technology. Prioritising Summary. LifePort. ® kidney transporter: A portable donor kidney transporter/ perfuser. November 24 – What to do after pumping begins. 28 – Removing a kidney from LifePort Kidney Transporter; removing used Perfusion Circuit after a case. 34 – 45 . The LifePort Kidney Transporter is a revolutionary method of transporting kidneys for transplantation: it is a portable, insulated perfusion transporter with.

Author: Kazraran Moogule
Country: Jordan
Language: English (Spanish)
Genre: Art
Published (Last): 23 November 2013
Pages: 82
PDF File Size: 19.89 Mb
ePub File Size: 17.85 Mb
ISBN: 197-1-57519-408-6
Downloads: 32448
Price: Free* [*Free Regsitration Required]
Uploader: Vonos

The Lifeport Kidney Transporter

Published online Dec 1. Hypothermic machine perfusion versus cold storage in the rescuing of livers from non-heart-beating donor rats. Can Urol Assoc J.

China Find articles by Cheng Zeng. Five-year experience with donation after cardiac death kidney transplantation in a Canadian transplant program: However, the limitation of our modification was that this prevention function of Lifeport could no longer be properly initiated.


Once the circuit was primed, the liver was connected and ready for perfusion under prime mode. Our Website uses cookies to improve your experience. By contrast, according to the preliminary results in lifelort present study, the prime mode of Lifeport could achieve continuous perfusion, which was indicated by the oscillogram with a high frequency and small wave range.

No significant difference was observed between the two regions.

Kamada N, Calne RY. The level of endothelin in the hepatic effluent every 3 h of the 6-h HMP period was assessed using a commercialized assay kit cat no. National Center for Biotechnology InformationU. The lack of effective integration of these equipment was the major obstacle associated with the portability of HMP, leading to restriction for its implementation. Influence of perfusate on liver viability during hypothermic machine perfusion.


During HMP, although the levels of ALT and LDH were significantly increased over the total 6-h time period, endothelin release, which is typically used to reflect the levels of cellular shear stress and pressure caused by HMP 25did not significantly increase.

Hepatic effluent was collected from the catheter cannulated in the suprahepatic vena cava every 3 h of the 6-h HMP period and the levels of alanine transaminase ALT and lactate dehydrogenase LDH were analyzed. The final problem needed to be solved was the measurement of portal inflow.

China Find articles by Yanfeng Wang. However, the major obstacle preventing large-scale experimental application of HMP for rat livers is a lack of a portable HMP system that is compatible with the size of rat livers. Conceptual and practical considerations.

During HMP, although a significant decrease was observed between 0 0. B Overall appearance of the modified HMP system. Compared with these results, the levels of OC in our experiment were lower but constant over the 6-h time period of HMP Fig. Hypothermic machine preservation in human liver transplantation: In the present study, a simple modification was made to the LifePort Kidney Transporter ,ifeport ensure HMP for rat liver while retaining portability.

The Lifeport Kidney Transporter – INDEX: Design to Improve Life®

Introduction To overcome the shortage of brain-dead donors kidneh liver transplantation, extended criteria donors ECDs have been used 1. To assess changes in morphology, samples were obtained and analyzed via hematoxylin and eosin staining of a peripheral biopsy following the completion of flush in situ pre-HMP sample and a peripheral biopsy at the end of HMP post-HMP lifeporr.


Although the automation of this system requires further modification, the present results suggest that, using the modified system, the demands of flow and pressure during continuous HMP via the rat portal vein can be met, while the dependability and portability of the LifePort are retained.

Joint impact of donor and recipient parameters on the trransporter of liver transplantation in Germany. The levels of sinusoidal dilatation, endothelial cell detachment and vacuolization were determined by two independent operators.

Experience with liver and kidney allografts from non-heart-beating donors. The system consisted of a rat liver container for perfusion that was installed tranpsorter the sterile drape of the LifePort Kidney Transporter 1. Combined with the results of ATP test A retrospective review of transplant data indicates that these perfused kidneys function better after transplant than statically stored kidneys. HMP, hypothermic machine perfusion.

Data trznsporter and sample collection The flow, pressure, intrahepatic resistance IRand temperature were recorded every 3 h for a total of 6 h during HMP.